30Extramammary Paget’s disease is a rare disorder and represents as infiltrated reddish patches or gray-white plaques which are eczematoid, crusty scaling, papillo-matous in the skin and mucous membrane of the anogenital or axillary regions, where generous apocrine glands exist.
At present 2 hypotheses are generally accepted in regard to pathogenesis. Woodruff and Richardson(1957) support that it is a carcinoma of epithelial origin, wherase by Weiner(1937), Dockerty and Pratt(1952) it is migrated into the skin from an underlying apocrine gland carcinoma. But many controversies have still been existed and never clarified.
The keratinizing squamous cell carcinoma, non-keratinizing cancer(basal cell epithelioma, Bowen’s disease and malignant amelanotic melanoma) and eczematous lesions make clinical diagnosis difficult. Thus a biopsy is necessary for a definite diagnosis. Also it must be histopathologically differenciated from Bowen’s disease and pagetoid type of malignant melanoma in situ. The treatments were not satisfactory with x-ray irradiation, topical therapy, desiccation, curettage except for deep and wide excision.
We have experienced a case of extamammary Paget’s disease occuring on the left inguinal, scrotal area and obtained satisfactory result following surgical excision & skin graft.
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